Research conducted by the Section of Vascular Surgery includes basic, translational and clinical investigations.
The laboratory of Mohamed Zayed, MD, PhD, studies the mechanisms that influence arterial collateral formation and peripheral arterial atheroprogression in the setting of diabetes. See lab website.
The laboratory of Sean English, MD, investigates the pathophysiology of abdominal aortic aneurysm (AAA) disease and its associated rupture. They are developing novel therapeutics, with a focus on halting AAA growth and preventing rupture. They are also developing noninvasive techniques for predicting AAA growth and/or rupture and providing more sophisticated modalities for AAA surveillance, in a patient-specific manner.
Clinical research is another active interest in the Section of Vascular Surgery, with ongoing projects on the endovascular treatment of aneurysmal and occlusive arterial disease conducted by members of the section. The section currently participates in multiple clinical trials of minimally invasive devices in collaboration with industry. Most recently, there has been increased emphasis on patient outcomes research with investigations evaluating the comparative effectiveness of open and endovascular procedures.
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